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About this chapter

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Interacting Drug	Effect	Level of Concern	Notes
Nitrates	Severe hypotension	High	Contraindicated
Alpha-blockers	Increased hypotensive risk	Moderate	Use cautiously
CYP3A4 inhibitors	Increased sildenafil levels	Moderate	Adjust dose accordingly
Other PDE5 inhibitors	Additive effects	High	Should not be combined

It includes the product name, active ingredient, strength, pharmaceutical form, route of administration, and marketing authorization holder for products in European Union member states. Bioequivalence to the EU reference product has been established for products listed in Annex IA, which are recommended to have their marketing authorizations maintained. It includes the product name, active i… B. Silde 1 A Pharma PAH (D), Sildenafil ratiopharm PAH (D), Sildenafil Stada (D, A), Sildenafil PAH mepha (CH) U. Gresser, C. H. Gleiter: Erectile Dysfunction: Comparison Of Efficacy And Side Effects Of The PDE-5 Inhibitors Sildenafil, Vardenafil And Tadalafil. : Effect of sildenafil citrate on the cardiovascular system. An Encyclopaedia of Chemicals, Drugs and Biologicals. : Oral sildenafil in the treatment of erectile dysfunction. : Sildenafil inhibits altitude-induced hypoxemia and pulmonary hypertension. : Oral sildenafil in infants with persistent pulmonary hypertension of the newborn: a pilot randomized blinded study. Park, Ian Qureshi, Ray Lee, Paul Dent, Rakesh C. Kukrejaa: Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction. ↑ Christopher Lee Colglazier, Paul G Sutej, Kenneth S O’Rourke: Severe refractory fingertip ulcerations in a patient with scleroderma: successful treatment with sildenafil.

Frequently Asked Questions

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Country	Legal Status	Prescription Requirement	Common Brands Available	Online Purchase Allowed
USA	Prescription-only	Yes	Hexal, Viagra, generics	Limited, regulated
UK	Prescription-only	Yes	Hexal, Pfizer	Yes
Germany	Prescription-only	Yes	Hexal, Generics	Yes

: Recreational use and misuse of phosphodiesterase 5 inhibitors.

Externe Links zu erwähnten Verbindungen

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4. Expert opinion

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Nicht-medizinische Verwendung

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• It is important to report any serious side effects.
• Consuming high-fat meals can delay drug action.
• Sildenafil doesn't protect against sexually transmitted infections.
• It’s vital to use as directed for safe results.
• Never use more than one dose in 24 hours.

230; books.google.ch ↑ Annie Potts, Nicola Gavey, Victoria M. Grace, Tiina Vares: The downside of Viagra: women’s experiences and concerns.

Rights and permissions

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2.5. Gastrointestinal disease

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Erektile Dysfunktion (ED)

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• The medication may cause a burning sensation or rash.
• It’s not recommended for use in women.
• Sildenafil is sometimes used off-label for pulmonary hypertension.
• Do not share your medication with others.
• Monitor blood pressure regularly during use.

↑ Kirk Makin: In rare move, Pfizer asks Supreme Court to reconsider ruling that killed Viagra patent In: The Globe and Mail, 15. ↑ Hélène D’Iorio: The Supreme Court of Canada holds Pfizer’s Viagra patent invalid. ↑ in-PharmaTechnologist.com: Viagra patent expires in June, says Brazilian court. ↑ Abeer Allam: Seeking Investment, Egypt Tries Patent Laws In: New York Times, 4. Senat (L 8 KR 80/05 ER). ↑ Axel Kleemann: Pharmaceutical substances: syntheses, patents, and applications of the most relevant AIPs.5.

• Do not drive or operate machinery after taking Sildenafil.
• It may cause temporary vision disturbances.
• Notify your doctor of any heart problems.
• Take the medication with water, not with a heavy meal.
• Keep out of reach of children.

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